Kholoud Shaban
Post-Doctoral Fellow
Dr. Shaban is a molecular biologist and microbiologist with extensive experience in synthetic biology, vector design, and the analysis of fluorescent reporters using flow cytometry and fluorescence microscopy. With over a decade of laboratory research experience, she brings deep expertise in in vivo animal models, immunological analyses, and vaccine development.
She is currently a postdoctoral researcher in the Slavcev Lab at the School of Pharmacy, University of Waterloo, where her work focuses on optimizing gene therapy production systems. Her research involves in vitro and in vivo evaluation of novel viral gene therapies targeting retinal and central nervous system (CNS) disorders, with the goal of advancing these therapies toward clinical trials.
Education
B.Sc. (Honors) Microbiology, Minor in Biochemistry. Kuwait University (2007)
M.Sc. Medical Microbiology. Kuwait University (2011)
Ph.D. Molecular and Cellular Biology, University of Guelph (2022)
Contact
PUBLICATIONS:
Reid Buchanan, Kholoud Shaban, et. al. 2025. Temporal wheat proteome remodeling by deoxynivalenol reveals novel detoxification signatures across cultivars. Molecular Cell Proteomics.
Kholoud Shaban, et. al. 2023. TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks. Current Genetics.
Kholoud Shaban, et. al. 2023. Evaluation of drug-free methods for the detection of gene silencing in S. cerevisiae. Biochemistry and Cell Biology Journal.
Andrew Dolson, Safia Mahabub Sauty, Kholoud Shaban, et al. 2021. Dbf4-Dependent Kinase: DDK-ated to post-initiation events in DNA replication. Cell Cycle.
Kholoud Shaban, Safia Mahabub Sauty, and Krassimir Yankulov. 2021. Variation, Variegation and Heritable Gene Repression in S. cerevisiae. Frontiers in Genetics.
Safia Mahabub Sauty, Kholoud Shaban, and Krassimir Yankulov. 2021. Gene repression in S. cerevisiae—looking beyond Sir-dependent gene silencing. Current Genetics.
Hollie Rowlands, Kholoud Shaban, Barret Foster, Yannic Proteau and Krassimir Yankulov. 2019. Histone chaperones and the Rrm3p helicase regulate flocculation in S. cerevisiae. Epigenetics & Chromatin
Hollie Rowlands, Kholoud Shaban, Ashley Cheng, Barret Foster, and Krassimir Yankulov. 2019. Dysfunctional CAF-I reveals its role in cell cycle progression and differential regulation of gene silencing. Cell Cycle.
Kholoud Shaban, Hanady Amoudy, Abu Salim Mustafa. 2013 Cellular Immune Responses to Recombinant Mycobacterium bovis BCG Constructs Expressing Major Antigens of Region of Difference 1 of Mycobacterium tuberculosis. Clinical and Vaccine Immunology.